SRSMC UMR 7565


Partenaires

CNRS


Rechercher

Sur ce site

Sur le Web du CNRS


Accueil > Pages Personnelles

KIRSCH Gilbert

Professeur

Equipe : HéCRIN
Tel  : 0387315295
E-mail : kirsch@univ-lorraine.fr
Adresse
Université de Lorraine
UMR CNRS 7565 SRSMC
Faculté des sciences et technologies BP 70239
54506 Vandoeuvre les Nancy cedex
 
 Domaine d’activité :
 
 
 
 
 
 
 
 
 
 

Publications

2018

Tittikpina, N. K., Nana, F., Fontanay, S., Philippot, S., Batawila, K., Akpagana, K., Kirsch, G., Chaimbault, P., Jacob, C., & Duval, R. E. (2018). Antibacterial activity and cytotoxicity of Pterocarpus erinaceus Poir extracts, fractions and isolated compounds. Journal of Ethnopharmacology, 212, 200–207.
toggle visibility

2017

Tittikpina, N. K., Atakpama, W., Pereki, H., Nasim, M. J., Ali, W., Fontanay, S., Nana, F., Ejike, C. E., Kirsch, G., Duval, R. E., Chaimbault, P., Karou, S. D., Batawila, K., Akpagana, K., & Jacob, C. (2017). ‘Capiture’ plants with interesting biological activities: a case to go. Open Chemistry, 15(1).
toggle visibility

2016

Griffin, S., Tittikpina, N., Al-marby, A., Alkhayer, R., Denezhkin, P., Witek, K., Gbogbo, K., Batawila, K., Duval, R., Nasim, M., Awadh-Ali, N., Kirsch, G., Chaimbault, P., Schäfer, K. - H., Keck, C., Handzlik, J., & Jacob, C. (2016). Turning Waste into Value: Nanosized Natural Plant Materials of Solanum incanum L. and Pterocarpus erinaceus Poir with Promising Antimicrobial Activities. Pharmaceutics, 8(2), 11.
toggle visibility
Huber-Villaume, S., Revelant, G., Sibille, E., Philippot, S., Morabito, A., Dunand, S., Chaimbault, P., Bagrel, D., Kirsch, G., Hesse, S., & Schohn, H. (2016). 2-(Thienothiazolylimino)-1,3-thiazolidin-4-ones inhibit cell division cycle 25 A phosphatase. Bioorganic & Medicinal Chemistry, 24(13), 2920–2928.
toggle visibility
Rouatbi, F., Askri, M., Nana, F., Kirsch, G., Sriram, D., & Yogeeswari, P. (2016). Synthesis of new spirooxindole derivatives through 1,3-dipolar cycloaddition of azomethine ylides and their antitubercular activity. Tetrahedron Letters, 57(2), 163–167.
toggle visibility
Seidel, C., Schnekenburger, M., Mazumder, A., Teiten, M. - H., Kirsch, G., Dicato, M., & Diederich, M. (2016). 4-Hydroxybenzoic acid derivatives as HDAC6-specific inhibitors modulating microtubular structure and HSP90α chaperone activity against prostate cancer. Biochemical Pharmacology, 99, 31–52.
toggle visibility
Talhi, O., Brodziak-Jarosz, L., Panning, J., Orlikova, B., Zwergel, C., Tzanova, T., Philippot, S., Pinto, D. C. G. A., Paz, F. A. A., Gerhäuser, C., Dick, T. P., Jacob, C., Diederich, M., Bagrel, D., Kirsch, G., & Silva, A. M. S. (2016). One-Pot Synthesis of Benzopyran-4-ones with Cancer Preventive and Therapeutic Potential. Eur. J. Org. Chem., 2016(5), 965–975.
toggle visibility
Tittikpina, N., Nana, F., Fontanay, S., Batawila, K., Akpagana, K., Kirsch, G., Duval, R., Chaimbault, P., & Jacob, C. (2016). Study of Pterocarpus erinaceus, a promising plant from Togo to treat infectious diseases. Planta Medica, 81(S 01), S1–S381.
toggle visibility

2015

Abdi, Y., Boutemeur-Kheddis, B., Hamdi, M., Talhi, O., Paz, F., Kirsch, G., & Silva, A. (2015). A One-Pot Diastereoselective Synthesis of 2-[Aryl(hydroxy)methyl]-6-methyl-2H-furo[3,2-c]pyran-3,4-diones: Crystallographic Evidence for the Furanone Ring Closure. Synlett, 26(12), 1749–1754.
toggle visibility
Bana, E., Sibille, E., Valente, S., Cerella, C., Chaimbault, P., Kirsch, G., Dicato, M., Diederich, M., & Bagrel, D. (2015). A novel coumarin-quinone derivative SV37 inhibits CDC25 phosphatases, impairs proliferation, and induces cell death. Molecular Carcinogenesis, 54(3), 229–241.
toggle visibility
Paegle, E., Belyakov, S., Kirsch, G., & Arsenyan, P. (2015). Addition of selenium(II) bromide to arylalkynylamides—a route to hypervalent T-shaped 10-Se-3 systems. Tetrahedron Letters, 56(30), 4554–4557.
toggle visibility
Ragno, R., Ballante, F., Pirolli, A., Iii, R. B. W., Patsilinakos, A., Hesse, S., Perspicace, E., & Kirsch, G. (2015). Vascular endothelial growth factor receptor-2 (VEGFR-2) inhibitors: development and validation of predictive 3-D QSAR models through extensive ligand- and structure-based approaches. J Comput Aided Mol Des, 29(8), 757–776.
toggle visibility
Ravez, S., Arsenlis, S., Barczyk, A., Dupont, A., Frédérick, R., Hesse, S., Kirsch, G., Depreux, P., & Goossens, L. (2015). Synthesis and biological evaluation of di-aryl urea derivatives as c-Kit inhibitors. Bioorganic & Medicinal Chemistry, 23(22), 7340–7347.
toggle visibility
Revelant, G., Huber-Villaume, S., Dunand, S., Kirsch, G., Schohn, H., & Hesse, S. (2015). Synthesis and biological evaluation of novel 2-heteroarylimino-1,3-thiazolidin-4-ones as potential anti-tumor agents. European Journal of Medicinal Chemistry, 94, 102–112.
toggle visibility
Sousa, J., Talhi, O., Rocha, D., Pinto, D., Almeida Paz, F., Bachari, K., Kirsch, G., & Silva, A. (2015). One-Pot Synthesis of Novel Highly Functionalized Furan-Based Polyphenolics. Synlett, 26(19), 2724–2729.
toggle visibility
Tittikpina, N. K., Ejike, C. E. C. C., Estevam, E. C., Nasim, M. J., Griffin, S., Chaimbault, P., Kirsch, G., Atakpama, W., Batawila, K., & Jacob, C. (2015). Togo To Go: Products And Compounds Derived From Local Plants For The Treatment Of Diseases Endemic In Sub-Saharan Africa. African Journal of Traditional, Complementary and Alternative medicines (AJTCAM), 13(1), 85–94.
toggle visibility

2014

Chaouni, W., Aadil, M., Djellal, A., & Kirsch, G. (2014). Synthesis of Methyl 3-Azidothieno[2,3- b ]pyridine-2-carboxylates and Application of the Huisgen Reaction. Zeitschrift für Naturforschung B, 69b, 509–518.
toggle visibility
Du, P., Viswanathan, U. M., Xu, Z., Ebrahimnejad, H., Hanf, B., Burkholz, T., Schneider, M., Bernhardt, I., Kirsch, G., & Jacob, C. (2014). Synthesis of amphiphilic seleninic acid derivatives with considerable activity against cellular membranes and certain pathogenic microbes. Journal of Hazardous Materials, 269, 74–82.
toggle visibility
Revelant, G., Gadais, C., Mathieu, V., Kirsch, G., & Hesse, S. (2014). Synthesis and antiproliferative studies of 5-aryl-2-(3-thienylamino)-1,3,4-thiadiazoles. Bioorganic & Medicinal Chemistry Letters, 24(12), 2724–2727.
toggle visibility
Valente, S., Liu, Y., Schnekenburger, M., Zwergel, C., Cosconati, S., Gros, C., Tardugno, M., Labella, D., Florean, C., Minden, S., Hashimoto, H., Chang, Y., Zhang, X., Kirsch, G., Novellino, E., Arimondo, P. B., Miele, E., Ferretti, E., Gulino, A., Diederich, M., Cheng, X., & Mai, A. (2014). Selective Non-nucleoside Inhibitors of Human DNA Methyltransferases Active in Cancer Including in Cancer Stem Cells. J. Med. Chem., 57(3), 701–713.
toggle visibility

2013

Lefranc, F., Xu, Z., Burth, P., Mathieu, V., Revelant, G., Velho de Castro Faria, M., Noyon, C., Garcia, D. G., Dufour, D., Bruyère, C., Gonçalves-de-Albuquerque, C. F., Van Antwerpen, P., Rogister, B., Hesse, S., Kirsch, G., & Kiss, R. (2013). 4-Bromo-2-(piperidin-1-yl)thiazol-5-yl-phenyl methanone (12b) inhibits Na+/K+-ATPase and Ras oncogene activity in cancer cells. European Journal of Medicinal Chemistry, 63, 213–223.
toggle visibility
Perspicace, E., Jouan-Hureaux, V., Ragno, R., Ballante, F., Sartini, S., La Motta, C., Da Settimo, F., Chen, B., Kirsch, G., Schneider, S., Faivre, B., & Hesse, S. (2013). Design, synthesis and biological evaluation of new classes of thieno[3,2-d]pyrimidinone and thieno[1,2,3]triazine as inhibitor of vascular endothelial growth factor receptor-2 (VEGFR-2). Eur J Med Chem, 63, 765–781.
toggle visibility
Rongved, P., Kirsch, G., Bouaziz, Z., Jose, J., & Le Borgne, M. (2013). Indenoindoles and cyclopentacarbazoles as bioactive compounds: Synthesis and biological applications. European Journal of Medicinal Chemistry, 69, 465–479.
toggle visibility
Valente, S., Xu, Z., Bana, E., Zwergel, C., Mai, A., Jacob, C., Meiser, P., Bagrel, D., Silva, A. M. S., & Kirsch, G. (2013). Reactivity of 4-Vinyl-2H-1-benzopyran-2-ones in Diels–Alder Cycloaddition Reactions: Access to Coumarin-Based Polycycles with Cdc25 Phosphatase-Inhibiting Activity. European Journal of Organic Chemistry, 2013(14), 2869–2877.
toggle visibility

2012

Datoussaid, Y., & Othman, A., Kirsch, G. (2012). Synthesis and Antibacterial Activity of some 5,5 ’ -(1,4-phenylene)-bis-1,3,4-Oxadiazole and bis-1,2,4-Triazole Derivatives as Precursors of New S -Nucleosides. S. Afr. J. Chem, 65, 30–35.
toggle visibility
Gadais, C., Hesse, S., & Kirsch, G. (2012). Regioselective Thorpe-Ziegler Cyclization of 3-O-Alkylated Thiophenes; Access to Aminothieno[3,2-b]furans and Aminothieno[3,4-b]furans. Synthesis, 44(18), 2964–2968.
toggle visibility
Pinto, T., Hrdina, R., Kirsch, G., Oliveira-Campos, A., Rodrigues, L., & Esteves, A. (2012). Synthesis of esters derived from 2,3,4-tri-O-benzyl-alpha-D-methylglucoside. ARKIVOC: archive for organic chemistry, VI, 185–193.
toggle visibility
Saidu, N. E. B., Valente, S., Bana, E., Kirsch, G., Bagrel, D., & Montenarh, M. (2012). Coumarin polysulfides inhibit cell growth and induce apoptosis in HCT116 colon cancer cells. Bioorg. Med. Chem., 20(4), 1584–1593.
toggle visibility
Seck, P., Thomae, D., Perspicace, E., Hesse, S., & Kirsch, G. (2012). Synthesis of new selenophene and thiazole analogues of the Tacrine series. Arkivoc, 2012(3), 431.
toggle visibility
Zwergel, C., Gaascht, F., Valente, S., Diederich, M., Bagrel, D., & Kirsch, G. (2012). Aurones: interesting natural and synthetic compounds with emerging biological potential. Nat Prod Commun, 7(3), 389–394.
toggle visibility